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doi: 10.1097/YIC.0000000000000130 190

it's about the small, consistent choices you make every day

Consistent with this, use of a reducing source such as -mercaptoethanol allows reversal of xCT-KO phenotype, as it has been reported couple decades ago by Bannai's group ( in vivo can explain the discrepancy with in vitro phenotype

Kumagai, A., Eisenberg, J

FOXO4, one of the members of this family, interacts with the p53 protein to help senescent cells avoid apoptosis

The inhibition of fatty acid metabolism via HIF increases intracellular lipid storage, and subsequently the sensitivity to iron-mediated cell death (84)