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In contrast, we employed COX-2 knockout mice and a selective COX-2 inhibitor (etoricoxib) to conduct a series of assays, ensuring target specificity for COX-2

10.3322/caac.21219 58 WeisbergerA

H 2 O 2 reacts with ferrous iron (Fe 2+ ) in the Fenton reaction generating the highly toxic hydroxyl radical (OH) which can damage all cellular macromolecules (Imlay, 2003, 2008)

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Fish oil is a major source of omega-3 fatty acids, which may have several health benefits

1 Introduction Cardiovascular diseases (CVDs) represent a group of disorders that significantly impact the heart and blood vessels, such as coronary artery disease (CAD), stroke, peripheral arterial disease, and congenital heart defects (5)