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Neuroprotective effect of diosgenin in a mouse model of diabetic peripheral neuropathy involves the Nrf2/HO-1 pathway

As a result, many scholars are concerned about when SPNFT technology can move from the laboratory and into practical commercial use

Emerging evidence suggests that Nrf2 can enhance the expression of rhythm-inhibiting genes such as cryptochrome 2 and Rev-Erb in the nucleus, thereby indirectly inhibiting transcription mediated by the CLOCK-BMAL1 complex [103]

It protects cells from oxidative stress, neutralizes free radicals, supports liver detoxification, and maintains the body's immune response

Genomic DNA was isolated using buffer (100 mM Tris-HCl, 5 mM EDTA, 0.2% SDS, 200 mM NaCl + proteinase K) and precipitation with isopropanol