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OS-induced mitochondrial damage in pyramidal neurons is considered a hallmark of mitophagy dysfunction in neurodegenerative diseases (Talebi et al., 2022)

There is no genetic test yet for hEDS

This might be supported by the identification of this protein in two proteomic studies of mitochondrial protein fractions (Table 3) (Heazlewood et al., 2004

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Increased lipid peroxidation marker concentrations, 8-isoprostane-F 2 , have also been found in ASD patients [113]

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