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Chebulinic acid, for example, activates the Nrf2 and MAPK signaling pathways to upregulate endogenous antioxidants like SOD and NQO1 (Wang et al., 2021)

Manage., 2024, 352, 120051 CrossRef CAS PubMed

GHRP-6 shows a similar profile

Furthermore, a clear dose-response relationship was observed, wherein higher doses were associated with greater symptomatic relief [140]

Fermentation could remarkably increase the polyphenol contents' bioavailability and bioaccessibility present in legumes

Although ROS generated under physiological conditions are not harmful, and likely play a signaling role, toxic or pathological conditions that lead to an impairment of mitochondrial function can increase the release of ROS