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The inflammatory markers interleukin (IL)1A, IL1B, and IL1R2 are significantly upregulated ( PRP shows promise in reproductive medicine by demonstrating the potential for endometrial regeneration, menstrual cycle restoration, improved follicle development, heightened endometrial receptivity ( 5 Possible clinical challenges of PRP as new agents Advantages of clinical applications (1): Multiple growth factors have a synergistic promoting effect ( Safety and Efficacy: (1) After the isolation of autologous venous blood, there is no rejection reaction or related immune rejection issues ( Table 1 shows the clinical trials of FDA-approved PRP therapy, which have been initiated for female reproductive and endocrine dysfunction

Novakova I, Subileau EA, Toegel S, Gruber D, Lachmann B, Urban E, Chesne C, Noe CR, Neuhaus W