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Among the 12 patients who underwent liver biopsy, lobular hepatitis was identified in 12 (100%), eosinophilic infiltration in 6 (50%), and cholestasis and bile duct injuries in 2 (16.7%)

When the gut lining becomes compromised, leaky gut and various other gut disorders can occur

In fact, reduced levels of miR-382 in cells led to an increased expression of CTTN, Rac1 and ARPC2, all players of actin cytoskeleton remodeling

Effects of treatment for psoriasis on circulating levels of leptin, adiponectin and resistin: a systematic review and meta-analysis

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Disclosures: Giuseppe Cullaro: Ocelot Bio: Consultant, Retro Sciences: Consultant, Kavish Patidar: Nothing to Disclose, Andrew Allegretti: Nothing to Disclose, Elizabeth Verna: Salix: Grant/Research Support, Jennifer Lai: Nestle Nutrition Institute: Grant/Research Support, Novo Nordisk: Consultant, Genfit: Consultant, Boehringer Ingelheim: Advisor 939 SOCIAL DETERMINANTS OF HEALTH AND METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE IN CHILDREN WITH OVERWEIGHT OR OBESITY Ananya Venkatesh 1 Nhat Thai 1 Patricia Ugalde Nicalo 1 Kimberly Newton 1 Cynthia Behling 2 Romeo Ignacio 1 Laura Bauman 1 Martha Smith 1 Jeffrey Schwimmer 1 , 1 University of California, San Diego, 2 Pacific Rim Pathology Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common pediatric liver disease