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Studies find increased expression of M1 macrophage markers and decreased expression of M2 markers in DW

Higher concentrations of kynurenic acid in CSF are associated with the slower clinical progression of Alzheimers disease

Age-related macrophage alterations are associated with carcinogenesis of colorectal cancer

By contrast, increasing GSH results in decreased SOCE

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In models of viral infection, the expansion of GLS-deficient CD8+ T cells was significantly reduced, further underscoring the importance of GLS activity in CD8+ T cell function