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The gut microbiome in coronary artery disease and heart failure: current knowledge and future directions

10.1016/j.drugalcdep.2011.10.026 105 LauE

While alternative administration routes, such as intravenous, intramuscular, nasal, percutaneous, and transdermal delivery, have shown promise in certain conditions, these methods can be invasive and uncomfortable for patients

The framework takes into account clinical benefits, value for money, societal and ethical considerations, and the economic feasibility of the health care intervention in Ontario

The higher rates in the diabetes population likely reflect the baseline GI motility alterations common in type 2 diabetes (diabetic gastroparesis, autonomic neuropathy) and the potential for additive GI effects with concomitant metformin use

S.AndrewsR.et al