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So et al

doi: 10.1183/13993003.00196-2017 55 GhoshACoakleyRDGhioAJMuhlebachMSEstherCRJr.AlexisNEet al

Cystathionine beta-synthase (CBS) deficiency is the only defect that consistently causes homocystinuria

writingoriginal draft preparation, D.I.C

Moreover, nonsteroidal anti-inflammatory drugs (NSAIDs), prototypic inhibitors of cyclooxygenase (COX) activity and PGE2 production, can trigger or worsen the disease (51, 52)