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Additionally, an intramuscular injection of vitamin B12 is given one week before the first dose and then every 9 weeks thereafter

SMARCA4, SMARCB1, and PBRM1 are frequently mutated in 10% of patients with non-small lung adenocarcinomas 7 , and in almost patients with rhabdoid tumors, epithelioid sarcomas 8,9 , or in 40% of renal clear cell carcinomas 7

Toxic effects can appear within 24 hours of exposure

Saikosaponin D inhibits peritoneal fibrosis in rats with renal failure by regulation of TGF1/BMP7/Gremlin1/smad pathway

Sorafenib significantly induces exspression of MT-1G messenger RNA and proteins, and activation of Nrf2 is critical for MT-1G expression induced after sorafenib treatment (Houessinon et al., 2016)

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