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doi: 10.1042/BST20190088 31 XuWWangYHouGWangJWangTQianJet al

B12 injections (hydroxocobalamin) are licensed medicines available on NHS prescription for treating confirmed B12 deficiency

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HQ has long been considered a gold-standard topical therapy for hyperpigmentation, and its effects typically become visible after several weeks of consistent use (often around 5-7 weeks according to clinical reports)