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Some phase III trials with anti-endothelial compounds have been done but the results have not been encouraging indicating that this could eventually be a rather difficult problem to solve [80]

The folate cycle is critically dependent on the availability of the essential micronutrient, vitamin B 12 (B 12 ), which is a required cofactor for the methionine synthase reaction in which homocysteine is converted to methionine through transfer of a methyl group from N-5-methyltetrahydrofolate (CH 3 -THF)

They may be given as a one-time treatment by your veterinarian or prescribed as a routine supplement to help maintain your pets levels

For formulators, this means enhanced safety and stability compared to free copper compounds

While you can take B12 and B complex together, its likely not necessary because the B complex will contain B12

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