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GSH may become compromised by oxidative stress induced by several factors in the course of serious infections, such as oxidative bursts by activated macrophages, hypergeneration of superoxide, TNFa-generated oxidative stress, induction of Cox-2 with increased arachidonate oxidations, and induction of iNOS with increased formation of nitric oxides and nitrosated GSH

Uncovering the trimethylamine-producing bacteria of the human gut microbiota

The possibility to study the early molecular effects of oxidative stress by Proteomics approach represents a powerful tool to generate new hypothesis for future studies

Potential biomarkers identified in this study could be used for early diagnosis and evaluation of ASD intervention, as well as to inform and target ASD pharmacological or nutritional treatment interventions