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The causes of this condition vary from person to person and their physical condition

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Liu R, Zou Z, Chen L, et al

10.1007/s00232-020-00127-0 Summary Keywords cell volume regulation, apoptosis, necrosis, pyroptosis, oxidative cell death, acidotoxic cell death, TRPM2, TRPM7 Citation Okada Y, Numata T, Sabirov RZ, Kashio M, Merzlyak PG and Sato-Numata K (2023) Cell death induction and protection by activation of ubiquitously expressed anion/cation channels

Mitochondrial dysfunction in PAH leads to increased ROS production, elevated oxidative stress, and metabolic reprogramming [97]