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Rather than moving to the next dose tier at 4 weeks, they hold each dose for 6 to 8 weeks before escalating

Li, R., Wang, G., Ding, Y., Tang, S., Chen, X., Dai, F., Wang, R., & Song, H

Other potential causes of B12 deficiency include: Gastritis Digestive diseases, such as Crohns disease and celiac disease Gastrointestinal surgery, such as gastric bypass Alcohol use Transcobalamin II deficiency, a rare genetic disorder that impairs the transport of vitamin B12 in the body Autoimmune disorder Complications/related conditions Is B12 deficiency serious or dangerous

The gap between those who see results and those who don't comes down to three things most success stories never mention: baseline metabolic health, adherence to caloric deficit, and realistic expectations about what lipotropics actually do versus what they're marketed to do

Santos Quaresma, M

3 RGN-259 Phase 3 Trial in Neurotrophic Keratopathy Sosne et al., International Journal of Molecular Sciences (2022) This Phase 3 randomized, placebo-controlled, double-masked clinical trial evaluated topical 0.1% RGN-259 (full-length recombinant T4 ophthalmic solution) in patients with neurotrophic keratopathy