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3.2.2 Hemopexin interactome in HL-60 cells The well controlled heme-HPX affinity chromatography of cell extracts containing biotinylated surface proteins from undifferentiated human HL-60 cells, together with an unbiased analysis using LC-MS/MS, revealed some additional members of the HL-60 HPX interactome, providing novel and unique information on the HPX system in immune cells (Supplementary Table S1)

This oral preparation would offer a more convenient and comfortable option for patients, potentially leading to better treatment compliance

Although this review has emphasized the promising potential of natural compounds, it is important to recognize that inconclusive or unfavorable dataparticularly from preclinical studies involving transgenic mouse and zebrafish modelsalso exist

In conclusion, the functions of specific genes in IBD involve intestinal epithelial cells and immune cells, with tissue- and cell-specific regulation of gene expression being key to the genetic susceptibility of IBD

Oxidative stress primarily refers to the process of oxidative damage resulting from an imbalance between oxidative and antioxidant systems in cells and tissues, leading to the accumulation of free radicals and ROS (41)