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The observed SCAN hyperconnectivity in PD was successfully replicated in the full samples of the PIPD dataset (two-tailed independent t = 3.5, P 0.05, FDR corrected)

2017;12:e0182773

In subsequent work, we will prioritize evaluating advanced delivery systems, including: intranasal administration to leverage direct nose-to-brain pathways

The spatial pattern of pressure-induced injury of RGCs correlates with the location of their axons within the ONH whereas other classes retinal neurons tend to be (at least initially) spared from IOP-induced injury (Figure 5) (8, 54)

The clinical significance of modest TMAO increases from L-carnitine supplements is not settled

We noted that we heard from interested parties that, when a hospital has negotiated a payer-specific negotiated charge that is based on an algorithm, an estimate displayed in dollars within the MRF is useful, particularly for making comparisons across hospitals (88 FR 82099)