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According to a prior study, PD patients were observed with much greater levels of 8-OHdG in peripheral blood leukocytes than those of the healthy controls, and this difference was connected with the severity of PD (Chen et al., 2009)

Dichloromethane layer can be used as is to dissolve PLGA polymer or can be dried using rotary evaporator and fresh dichloromethane is added to suspend the DAA-GSH-AuNCs and dissolve PLGA

The use of pembrolizumab, an anti-PD1 antibody, is under investigation in some clinical trials (NCT02359565 and NCT06514898) in recurrent groups 3 and 4, but results have not been published yet

UV-Vis, ultravioletvisible spectrometry

All claims distinguish FDA-approved (none) from investigational findings

The rhodamine moiety, which served as the detection unit for Fe 3+ , also acted as the energy acceptor