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++ Under 425.652(a)(8)(iv), if an ACO is eligible to receive a prior savings adjustment and the regional adjustment, expressed as a single value as described in 425.656(d), is positive, the ACO will receive an adjustment to its benchmark equal to the higher of the following: Under 425.652(a)(8)(iv)(A), the positive regional adjustment amount

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The calculation of normal mean has to be performed and updated with every fresh batch of reagents to account for the deviation in the control sample