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This metabolic state is similar to the highly active metabolism observed in many established (often virus-transformed) cell lines which (as pointed out above) are in general excellent host cells for most IBPs

Common alopecia symptoms include patches of hair loss, nail changes, and rapid shedding in localized areas, which differ from other types, such as androgenetic alopecia or telogen effluvium

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Eprenetapopt, which could reactivate mutant forms of p53 and induce ferroptosis by GSH depletion, is currently being tested in the clinical trials involving patients with acute myeloid leukemia (NCT03931291) [87]