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The pathogenesis of HACE is complex, with vascular edema being one of the most widely accepted mechanisms [5]

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This method is considered minimally invasive, as it involves injecting the solution into the affected area of the face, and the patient only feels minor discomfort

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Peptide injections should be avoided or used cautiously in patients with: Active or recent cancer Pregnancy or breastfeeding Uncontrolled thyroid, adrenal, or pituitary disorders Severe cardiovascular disease (peptide-specific) Known hypersensitivity to peptide components Significant autoimmune disorders (case-by-case) How to Inject Peptides Safely A frequent question from patients asks: Is injecting peptides safe