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the normal physiologic functions, and protection against pathogenic microbes and animal herbivores, and 2

doi: 10.1016/j.numecd.2014.01.002 2 AmarJ.BurcelinR.RuidavetsJ

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doi: 10.1016/j.neuint.2018.11.020 34 UgaldeVContrerasFPradoCChovarOEspinozaAPachecoR

Berberine should be avoided during pregnancy and breastfeeding due to potential risks to the infant, including concerns about effects on bilirubin metabolism in newborns