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Nitric oxide inhibits 5- reductase conversion of testosterone to DHT Dual wavelength LEDs reduce the conversion of testosterone to DHT by epithelial cells in vitro in vitro Step 1: Illuminate Cells Step 2: Add testosterone and/or finasteride Step 3: Competitive DHT ELISA Dual wavelength LED light induces NO and ROS production in epithelial cells in vitro in vitro Step 1: Add DAF-FM dictate (NO) or CellROX Deep Red Reagent (ROS) Step 2: Illuminate cells Step 3: Fluorescence microscopy Conclusions Dual wavelengths of 620 nm and 660 nm visible light maximally stimulate the production of reactive oxygen species and nitric oxide, decreasing the production of DHT in vitro

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Similarly, qualitative analysis of search strategies corroborated these findings (Fig

10.1007/978-3-319-66682-2_9 Glutathione in Plant Growth, Development, and Stress Tolerance 24 ChronopoulouE.GeorgakisN.Nianiou-ObeidatI.MadesisP.PerperopoulouF.PouliouF.et al (2017b)