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Pharmacokinetic and pharmacodynamic interactions between these two agents remain entirely unstudied

Jul 2013;178(7):792-8

The identified genes were categorized into three groups: 1) genes likely involved in housekeeping functions manifesting pleiotropic effects on multiple metabolites, 2) genes previously known to be involved in pathways for metabolites, and 3) novel genes which we have now genetically linked to specific metabolic pathways for metabolites

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Patients with gastrointestinal malignancies often experience malnutrition and metabolic disturbances, resulting in immune dysfunction, cytokine dysregulation, and endocrine abnormalities

Antunovic, M