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Nat Rev Cancer (2017) 17:70924

It works through a completely different mechanism than stimulant-based supplements or appetite suppressants

Key Safety Differentiators No IGF-1 elevation: AOD-9604 does not stimulate IGF-1, meaning it avoids risks such as organ/tissue overgrowth or acromegaly No glucose disruption: Clinical data shows it does not impair insulin sensitivity or worsen blood sugar regulation Comparable to placebo: In obesity trials, the incidence of adverse effects was similar to placebo groups, underscoring its tolerability Legal Status of AOD-9604 United States: AOD-9604 is not FDA-approved as a drug, dietary supplement, or weight loss therapy

[DOI] [PMC free article] [PubMed] [Google Scholar] 358.de Zlicourt, A

Inhibition of fatty acid synthase with FT-4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non-alcoholic fatty liver disease: results from two early-phase randomized trials

Furthermore, the 2mg strength allows researchers to measure accurate quantities for controlled laboratory studies