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The duration of the trials ranged from four weeks to 36 months and the comparison groups were given either a placebo or a multivitamin without vitamin K

Some supplements, such as multivitamins or vitamin B12 tablets, also contain vitamin B12

Ingredients include B6, Methionine, Inositol, Choline, Thiamine, and Riboflavin

TB-500 interacts with G-actin through the conserved LKKTET motif, influencing actin polymerization dynamics, cytoskeletal organization, and actin-associated signaling pathways

Available online at: (accessed on 08 January, 2025)

Moderate and severe TBI carries substantially higher risks of long-term disability, including impaired memory, executive function deficits, emotional dysregulation, and increased vulnerability to neurodegenerative disease later in life