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On the basis of these results, together with studies reporting reduced Ser plasma levels in cachectic CRC-bearing mice [25, 26] and body mass depletion in cancer-bearing patients [27], we hypothesized that tumor-induced alterations in Ser availability could contribute to muscle wasting during cancer cachexia

Gene editing technologies, particularly CRISPR-Cas9, allow precise genome modifications in animals, reducing immune rejection and improving organ compatibility

A G protein-coupled receptor responsive to bile acids

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[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Yang C., Zhong Z.-F., Wang S.-P., Vong C.-T., Yu B., Wang Y.-T