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Targeting PUFA-related pathways inhibits ferroptosis Finally, inhibition of PUFA synthetic pathways may be protective against IR-induced tissue injury (Table 5)

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Studies have also found that as DR progresses, RMCs gradually start to undergo apoptosis, and the frequency of apoptosis is rapidly accelerated due to a decrease of protective cytokines such as BDNF and GDNF ( Under normal conditions, glial fibrillary acidic protein (GFAP) is primarily expressed by retinal astrocytes, but not by RMCs (Sanchez et al., 2022)

11,29 Results from the double-injection group further confirmed the safety of repeated DPSC administration in vivo

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Demonstration of OspC type diversity in invasive human Lyme disease isolates and identification of previously uncharacterized epitope that defines the specificity of the OspC murine antibody response