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Fluorescence intensity is calculated as mean fluorescence channel values using the CellQuest Software (Becton Dickinson)

In PD mice, both intravenous and intranasal Pu-Exos-PR markedly improve motor and non-motor symptomsincluding spontaneous activity, motor coordination, and depressive-like behaviorwhile reducing dopaminergic neuron degeneration, increasing Nissl body density, and enhancing TH expression, indicative of improved neuronal function

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doi: 10.3390/nu6126020