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The cells transduced with either the HOXC8-overexpressing or mock control vector were subjected to drug selection with 10 g/ml hygromycin for one month, resulting in the establishment of stable HOXC8-overexpressing cell lines (HOXC8-imESCs) and corresponding mock control lines (Control-imESCs)

However, the GI side effect burden at 8-12 mg retatrutide is substantially higher than tirzepatide at 10-15 mg

(2023) 83:35203532.e7

Balduini A, Di Buduo CA, Malara A, et al