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Sci Adv Mater

As a result, the balance between cell proliferation and apoptosis is disrupted, contributing to gastric carcinogenesis ( waf1/cip1 , proapoptotic protein Bax-1 and cleaved caspase 3 but also reversed the increase in the cell proliferation markers including cyclin D1 and PCNA, suggesting that lycopene protects the gastric mucosa from smoking-induced damage through p53-dependent cell cycle control and apoptosis, and may counteract the development of gastric cancer associated with smoking (Figure 3)

Weak for other peptides based on animal models only

Exogenous melatonin replaces what is missing, but it does nothing to restore the gland itself

A DNA nanocomplex containing cascade DNAzymes and promoter-like Zn-Mn-Ferrite for combined gene/chemo-dynamic therapy

Understanding where CagriSema and tirzepatide sit relative to other emerging therapies provides essential context for informed decision-making