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Several medical reports, regulatory advisories, and reviews have documented severe, potentially life-threatening reactions tied to injectable glutathione especially when done in unregulated settings or with contaminated/inappropriately compounded products

IT DFO could potentially cause neurotoxicity if the local concentration is too highhigh doses of systemic DFO have been associated with neurotoxic effects (e.g., hearing loss, seizures) (Zhang et al., 2025), and these risks would potentially be higher through direct CNS exposure

doi: 10.1002/14651858.CD007807.pub4 189 AgarwalAGuptaSSharmaRK

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