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I want to be very clear about that upfront

A fungal immunotherapeutic vaccine (NDV-3A) for treatment of recurrent vulvovaginal candidiasis-A phase 2 randomized, double-blind, placebo-controlled trial

NADPH is a critical reductant produced during immune metabolism, maintaining the function of intracellular antioxidant systems (e.g., thioredoxin and glutathione systems) and bidirectionally regulating ROS production and clearance in certain cells such as macrophages 143,144,145,146

Kleines M, Schellenberg K, Ritter K

This approach presents promising therapeutic opportunities for AD management (Table I

Curated supporting actives may include (but are not limited to): niacinamide (for barrier function and brightening synergy), alphaarbutin (additional tyrosinase modulation), and stable antioxidants (vitamin E derivatives) to protect both skin and glutathione from oxidative breakdown