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Full-length transcript sequences were aligned to the reference genome (ASM1485139v1) with alignment rates exceeding 99% across all tissues, yielding 10 million high-confidence transcripts for male tissues (testis and muscle) and 8 million for female ovarian tissue, thereby establishing a robust dataset for isoform-level analyses (Table 1)

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Abstract Parkinsons disease (PD) is a common neurodegenerative disorder caused by a spread of misfolded -synuclein and ascending neuronal degeneration mainly in dopaminergic neurons, leading to progressive nigrostriatal dysfunction and disruption of other pathways

Rahman, I., Kode, A

Y.WangH.et al (2021)

To this end, the Pmc4 mediator subunit was fused to a degron, and we found that IAA17 in combination with the two F-box proteins atAFB2 and osTIR1 was most effective (Supplementary Fig