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Cellular defenses against oxidative stress predominantly rely on the nuclear factor erythroid 2-related factor 2 (Nrf2), which orchestrates the expression of various antioxidant proteins and detoxification enzymes, including those involved in glutathione (GSH) synthesis, crucial for maintaining cellular homeostasis (55, 56)

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Most studied accessions exceed FAO/WHO (1991) essential amino acid requirements for children aged 25 years (Akin Idowu et al., 2013), although some reports note tryptophan or valine may be limiting in certain samples (Sidorova et al., 2023)

Committee on the Long-Term Health and Economic Effects of Antimicrobial Resistance in the United States

The effects of phytoestrogens on breast cancer may be also caused by their ability to inhibit local estrogen synthesis, induce epigenetic changes, and suppression of ER signaling pathways [68, 69]