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Overt vitamin B6 deficiency is rare, but approximately 10 percent of Americans may have inadequate B6 status, and it often occurs with deficiencies in other B vitamins like folate and B12

Vitamin B12 Hydroxocobalamin Each 2ml vial contains: B12 Hydroxocobalamin 5000mcg Sodium acetate hydrate, sodium Chloride, water for injection, acetic anhydride All products are Pharmaceutical Grade and manufactured to the highest standards

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Furthermore, prior to the onset of motor symptoms, over half of PD patients experience non-motor symptoms such as chronic constipation due to enteric nervous system dysfunction [91]

10.1371/journal.pone.0175549 69 RabyK