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In support of synergistic interactions, Bassil and colleagues demonstrated that the unilateral hippocampal injection of mouse syn PFF (mPFF) into the aggressive 5xFAD amyloid model leads to more severe and widespread syn pathology, hyperphosphorylated tau detection, hippocampal and midbrain neuronal loss, and cognitive and motor deficits [217]

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ROS promotes Th17 differentiation and IL-17 production through activation of the RORt and STAT3 pathways

Cuprizone intoxication induces cell intrinsic alterations in oligodendrocyte metabolism independent of copper chelation