glutathione reductase extract antioxidant pathway mediated by in response to Glutathione reductase (3D schematic representation)

56 These results highlight the possibility that genetic variation may have significant effects on susceptibility toward cancer

CHORD-SGT1 (CS) domain

Epigenetics refers to the molecular modifications on DNA and chromatin that alter gene expression without changing the DNA sequence (Li, 2021)

& Dorsett, D

Ishizawa J, Kojima K, Dilip A, Ruvolo V, Carter BZ, Allen JE, Neelapu SS, McDonnell T, Talekar M, El-Deiry WS, Kwak LW, Andreeff M

crude polysaccharides enriches beneficial gut bacteria (e.g., Leuconostoc lactis and Akkermansia muciniphila ) and elevates butyrate levels, enhancing intestinal barrier integrity, modulating amino acid biosynthesis pathways and antioxidant enzyme activities, thereby alleviating high-altitude exposure-induced oxidative stress damage and inflammatory responses (Liu et al., 2024)