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DOI: 10.1016/j.neuroscience.2016.11.001 108

In vitro studies have documented that GHK-Cu treatment (1-10 M) increases proliferation of outer root sheath keratinocytes by 30-60% and dermal papilla cells by 20-40%, cell populations critical for hair shaft formation and follicle cycling regulation

This aligns with integrative medicine principles of restoring function rather than substituting for it

PRMT5 utilises the universal methyl donor S-adenosylmethionine (SAM) to methylate arginine residues of protein substrates and regulate their activity, notably histones to regulate transcription