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Karanth, Shuofei Sun, Huanjing Bi, Kaiming Ye, Sha Jin Scientific Reports.2021;[Epub] CrossRef A Review of Current Trends with Type 2 Diabetes Epidemiology, Aetiology, Pathogenesis, Treatments and Future Perspectives Josh Reed, Stephen Bain, Venkateswarlu Kanamarlapudi Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2021

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The Smad family of proteins are intracellular signalling proteins that are directly involved in TGF- signalling, as well as members of several protein families such as BMP, which regulate osteoblast and osteoclast functions and play key regulatory roles in bone remodeling [55, 56]