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Efficacy and safety of lenzumestrocel (neuronata-R(R) inj) in patients with amyotrophic lateral sclerosis (ALSUMMIT study): study protocol for a multicentre, randomized, double-blind, parallel-group, sham procedure-controlled, phase III trial

2014;42:W2631

As a metabolic component in organisms, the multifaceted role of the carnitine pool in physiology and pathology has gradually received increasing attention

It can help transport fatty acids within the cell to the mitochondria, where they are converted into energy

For example, reducing the use of pulmonary surfactant in children with neonatal respiratory distress syndrome ( in vivo studies, incorporating long-term neuro-developmental follow-up, are essential to rigorously evaluate the therapeutic potential of L-carnitine/acetyl-L-carnitine in protecting the vulnerable developing brain following HIE ( In addition, the theoretical effect of L-carnitine is not limited to the above mentioned clinical applications

Deficientul secundar de Carnitin ce poate aprea datorit anumitor tulburri (cum ar fi insuficiena renal cronic) sau n condiii speciale (de exemplu, utilizarea anumitor antibiotice), care reduc absobia carnitinei sau mresc secreia acesteia