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The authors observed a decline of eGFR of 2.2 4.8 ml/min/1.73 m 2 per year in the placebo group and an improvement in eGFR in the pirfenidone 1200-mg group with a net increase of + 3.3 8.5 ml/min/1.73 m 2 over the span of 54 weeks

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Additional metabolic pathways and regulatory factors also influence cellular susceptibility to ferroptosis

However, due to the lack of standardized protocols, the microbial communities of patients with psoriasis were hardly comparable among the various study results, and it was difficult to confidently identify changes in the microbial communities associated with the psoriasis disease status

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Dynamic and high-resolution metabolic imaging of hyperpolarized [1-13C]-pyruvate in the rat brain using a high-performance gradient insert