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Selenium functions as an antioxidant through the activity of selenoproteins Although the importance of Se to health is not fully understood, one well-characterised function of Se is its ability to mitigate oxidative stress through antioxidant-functioning selenoproteins (Table 1), including the well-studied glutathione peroxidase (GPx) and thioredoxin reductase (TrxR) families ( Reference Hamilton and Tappel 18 , Reference Sordillo and Aitken 19 )

Mechanistically, curcumin modulates several key inflammatory pathways

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7 macrophages via NF-B and MAPKs signal pathways

Owing to their diverse phytochemical composition, plant-based remedies offer therapeutic benefits in the management of functional GI disorders such as dyspepsia, constipation, diarrhea, indigestion, IBS, GERD, and peptic ulcers

With that comes intense degrees of OCD, ritualistic behaviors, compulsions, obsessions, and intrusive thoughts