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244,245 DJ-1 also binds to the DNA-binding domain of p53, diminishing the DNA-binding affinity of p53 and inhibiting the expression of p53 target genes in a manner that relies on the oxidation of cysteine 106

Regulatory status: The FDA determined in 2022 that BPC-157 raises concerns that preclude its use in compounded preparations, placing it on the list of substances that may not be compounded under Sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act