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The dose component would move beyond simple quantity (mg) to focus on bioavailability from the food matrix and defining the precise biphasic dose-response curve to identify the optimal hormetic zone

10.1007/978-3-319-09614-8_7 198 StickelF.DatzC.HampeJ.BatallerR

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This suggests that the gut macrobiotic and its metabolites are engaged in the progression of atherosclerosis, and also that dysbiosis of gut flora is linked with systemic inflammation (Drosos et al., 2015)

96 recapitulated spatiotemporally each of the main steps of retinal development observed in vivo during the formation of three-dimensional retinal cups that contain all major retinal cell types arranged in their proper layers