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This makes it a potential therapeutic option for conditions such as inflammatory bowel disease (IBD), peptic ulcers, and gastroesophageal reflux disease (GERD), where maintaining gut health is paramount for symptom management and overall well-being

10.18632/oncotarget.23187 76 LiJ.MinczukK.MasseyJ

4 Molecular mechanism of intestinal barrier damage 4.1 TLR signaling pathway Toll-like receptor (TLR) is an innate immune pattern recognition receptor, promptly triggering intracellular signaling cascades upon detection of pathogen-associated molecular patterns (PAMPs), including proteins, nucleic acids, and lipids derived from invading pathogenic microorganisms