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Xiang T, Du L, Pham P, Zhu B, Jiang S

Introduction Glutathione S -transferases (GSTs) are a family of enzymes that conjugate reduced glutathione (GSH) to target molecules in the phase II detoxification of xenobiotic metabolism ( Here we examined the mechanisms of how GSTM1 regulates astrocyte transcriptional program in response to pro-inflammatory signaling and further addressed the impact of GSTM1 loss-of-function on neurons during acute brain inflammation following a systemic injection of lipopolysaccharides (LPS)

Moreover, aminosterols exert their anti-angiogenic action by inhibiting pro-angiogenic signaling pathways through blocking the activity of VEGF (vascular endothelial growth factor) and bFGF (basic fibroblast growth factor), two essential factors associated with neovascularization of plaques

C., & Nwankwo, C

Heat stress attenuates free radical release in the isolated perfused rat heart

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