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The highly acid gastric environment plays a key role in Cbl absorption as acidity and pepsin allow Cbl release contained in food

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Precision medicine focuses on designing targeted interventions based on individual patient characteristics, including genetic profile, microbiota composition, and disease phenotype, to enhance therapeutic outcomes and minimize adverse effects

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However, administration of acetazolamide decreased the urine aldosterone levels under hypoxia stress with respect to hypoxia exposed group

Similarly, the reduced content of GSH and decreased activity of antioxidant enzymes in the intestine (decreased GR, GPx and SOD activity) (Reference Chen, Feng and Jiang34) and gills (decreased GR, GPx, SOD and CAT activity) (Reference Chen, Feng and Jiang35) of riboflavin-deficient fish have been reported