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it is costly and may carry risks of headaches, anaphylactic shock, meningitis, or infectious disease

14-3-3 proteins are common phosphorylation binding proteins that mediate various proteinprotein interactions (PPIs) and implicating this class of protein in oligomeric state maintenance of GS leaves open the possibility that this class of proteins could be playing a chaperone-like function for GS more broadly

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Watanabe N, Mo F, McKenna MK

following a major trauma resulting in gram-negative sepsis and multi-organ failure (MOF), or gradually leading to chronic inflammatory diseases